This integrated mixing-granulation system completes blending, moistening, and granulation in a single operation, achieving high-efficiency processing cycles of 8-15 minutes. It produces granules with exceptional uniformity and optimal flow characteristics post-drying. Short mixing times minimize frictional heat generation, making it ideal for temperature-sensitive materials. The fully enclosed design eliminates airborne contamination and cross-contact risks. Constructed with pharmaceutical-grade 316L stainless steel featuring zero dead-leg geometry, it exceeds GMP certification requirements. Comprises six core components: main unit, reducer, discharge mechanism, chopper assembly, control cabinet, and counterweighted lid – all integrated with multi-point safety interlocks for fail-safe operation.

Features

1.Siemens PLC process control: touchscreen HMI enables programmable management of temperature, humidity, cycle time, and speed via pre-validated recipes.

2.Patented 3D Z-Blade technology: CAD-engineered agitators maintain 0.5-1mm clearance from vessel walls eliminating material buildup, reducing fines content by >8%. Laser-cut stainless steel choppers ensure vibration-free operation at high speed.

3.Anti-condensation ventilation: roof-mounted dehumidification system prevents moisture droplet formation and powder loss.

4.Permission-based safety system: password-protected start-up with lid-lock interlocking ensures operator safety during maintenance.

5.Dual-seal shaft protection: combined gas-lip and oil-seal technology eliminates shaft leakage.

6.Single-pot processing advantage: 400% productivity gain versus batch transfer systems. Produces dense, monodisperse granules with adjustable bulk density, ideal for TCM formulations with extreme API-excipient density differentials.