Introduction
Powdered material is loaded into the processing chamber where atomized binder solution is sprayed, causing particles to agglomerate into nuclei during the nucleation phase. These nuclei are dried and sieved and reintroduced with additional powder and binder spray, undergoing precision layering to form perfectly spherical pellets. Finished pellets can be further coated in the same chamber by applying atomized film-coating solutions to achieve uniform, continuous coating layers.
Features
1.Zero excipient restrictions: compatible with all standard pelletization excipients.
2.Multilayer functional pellets: enables precision manufacturing of controlled-release multi-layered pellets.
3.Pharmaceutical-grade sphericity: produces pellets with exceptional roundness (≥0.95 sphericity) and optimized dissolution profiles.
4.Integrated 3-in-1 processing: combines nucleation, pellet growth, and coating in a single platform.
5.Advanced turbulence engineering: proprietary vortex generators and deflectors optimize particle trajectory for ≥98% yield.
6.Bridging-free powder feed: auger feeder with anti-caking agitator ensures continuous, consistent material delivery.
7.Precision vertical adjustment: manual screw lift mechanism enables millimeter-accurate positioning with fail-safe locking.
8.Automated process control: touchscreen HMI + PLC system with variable frequency drive for stepless speed regulation.
9.Comprehensive safety compliance: full interlock protection meets GMP and CE safety requirements.
Technical Parameter
Item|Unit\Model |
ZC-400 |
ZC-500 |
ZC-750 |
ZC-1000 |
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Pellet Diameter |
mm |
0.2 |
0.5 |
2.0 |
5.0 |
||
Capacity(placebo pellets) |
Kg/batch |
≤2.5 |
≤10.0 |
≤20.0 |
≤50.0 |
||
Layering Ratio |
—— |
≤2 |
|||||
Pellet Diameter |
Min/batch |
0.25~25 |
|||||
Spheronization Plate Ø |
mm |
300 |
500 |
700 |
1000 |
||
Main Motor Power |
kW |
1.5 |
3 |
7.5 |
11 |
||
Blower Power |
kW |
0.75 |
1.5 |
2.2 |
4 |
||
Exhaust Fan Power |
kW |
0.55 |
0.75 |
1.5 |
2.2 |
||
Rotational Speed |
RPM |
50~1400 |
50~1400 |
50~1200 |
50~400 |
||
Steam Consumption |
MPa |
0.4~0.7 |
|||||
Kg/h |
5 |
8 |
12 |
14 |
|||
Compressed Air |
MPa |
0.4~0.6 |
|||||
m³/min |
0.5 |
0.7 |
0.9 |
1.1 |
|||
Operating Temperature |
℃ |
Indoor automatic temperature adjustment -100℃ |
|||||
Noise Level |
dB |
≤60 |
|||||
Dimension (L×W×H) |
mm |
760×700×1133 |
1100×860×1055 |
1400×1150×1359 |
1800×1300×1400 |
||
Net Weight |
Kg |
300 |
450 |
600 |
1600 |